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PJ-34 hydrochloride (synthetic) ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50=20nM compared to EC50=200µM of the prototypical PARP inhibitor 3-aminobenzamide). Inhibits peroxynitrite-induced cell necrosis (EC50=20nM). Has significant, dose-dependent, anti-inflammatory effects in a variety of local inflammation models and provides cardioprotection by decreasing myocardial infarct size.
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PJ-34 hydrochloride
Supplier: Thermo Scientific Chemicals
A cell-permeable, water-soluble phenanthridinone-derivative that acts as a potent inhibitor of poly(ADP-ribose) polymerase
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