- Type d'anticorps:Primaire
- Nom de l'antigène:hydrogen exchanger 3
- Clonalité:Polyclonal
- Conjugaison:Alexa Fluor® 680
- Hôte:Rabbit
- ImmunoChimie:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Réactivité:
- Western blot:Yes
- Environmentally Preferable:
- Épitope:301-400/834
- Formulaire:Liquid
- Synonymes antigène:MGC126720|Solute carrier family 9 sodium/hydrogen exchanger, isoform 3|NHE3|Solute carrier family 9 member 3|SLC9A 3|Slc9a3|MGC126718|Solute carrier family 9 sodium/hydrogen exchanger, member 3|Sodium/hydrogen exchanger, apical epithelial|NHE-3|Sodium/hydrogen exchanger 3|SL9A3_HUMAN|NHE 3|Na+/H+ exchanger 3|Sodium
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:93 kDa
- Température de stockage:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Température de transport:4 °C
- Immunogène:KLH conjugated synthetic peptide derived from human NHE3
- Tested applications:ICC
- Purification:Purified by Protein A
- Type de conditionnement:Vial
- Cdt:100 µl
NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localises to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Type: Primary
Antigen: hydrogen exchanger 3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 301-400/834
Host: Rabbit
Isotype: IgG
Reactivity: