- Type d'anticorps:Primaire
- Nom de l'antigène:RIMS3
- Clonalité:Polyclonal
- Conjugaison:Alexa Fluor® 750
- Hôte:Rabbit
- ImmunoChimie:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Réactivité:
- Western blot:Yes
- Environmentally Preferable:
- Épitope:21-120/308
- Formulaire:Liquid
- ID de gène:9783
- Synonymes antigène:RIM3|NIM3|RIMS3_HUMAN|RIM 3|NIM 3|Regulating synaptic membrane exocytosis protein 3|RIMS-3|RIMS 3|RIMS3|Rab 3 interacting molecule 3|Regulating synaptic membrane exocytosis 3|RIM3 gamma
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:33 kDa
- Température de stockage:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Température de transport:4 °C
- Immunogène:KLH conjugated synthetic peptide derived from human RIMS3
- Tested applications:ICC
- Purification:Purified by Protein A
- Type de conditionnement:Vial
- Cdt:100 µl
Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca²⁺ regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. localised to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.
Type: Primary
Antigen: RIMS3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/308
Host: Rabbit
Isotype: IgG
Reactivity: