Specifications
- Type d'anticorps:Primaire
- Nom de l'antigène:G protein beta 3/GNB3
- Clonalité:Polyclonal
- Conjugaison:Alexa Fluor® 680
- Hôte:Rabbit
- ImmunoChimie:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Réactivité:
- Environmentally Preferable:
- Épitope:81-180/340
- Formulaire:Liquid
- ID de gène:2784
- Synonymes antigène:SG|Transducin beta chain 3|IG|Tsubunit beta 3|Hypertension associated protein|GBB3_HUMAN|Gnb3|Guanine nucleotide binding protein G protein, beta polypeptide 3|Guanine nucleotide binding protein G
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:37 kDa
- Température de stockage:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Température de transport:4 °C
- Immunogène:KLH conjugated synthetic peptide derived from human G protein beta 3
- Tested applications:ICC
- Purification:Purified by Protein A
- Type de conditionnement:Vial
- Cdt:100 µl
Specifications
About this item
G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
Type: Primary
Antigen: G protein beta 3/GNB3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 81-180/340
Host: Rabbit
Isotype: IgG
Reactivity: