Spécifications
- Type d'anticorps:Primaire
- Nom de l'antigène:Aconitase 1
- Symbole de l'antigène:ACO1
- Clonalité:Polyclonal
- Conjugaison:Cy5®
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Environmentally Preferable:
- Adsorption croisée:No
- Formulaire:liquid
- ID de gène:48
- Synonymes antigène:IRP1|IREBP1|HEL60|ACONS|IREB1|IREBP
- Modification:phospho-Ser138
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Température de stockage:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Température de transport:4°C
- Purification:Purified by Protein A
- Cdt:100 µl
Spécifications
À propos de cet article
Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ACO1
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat