X-VIVO™ chemically defined, serum-free haematopoietic cell media provide nutritionally complete and balanced environments for a variety of cells, including lymphokine activated killer (LAK) cells, peripheral blood lymphocytes (PBL), and tumour infiltrating lymphocytes (TIL).

These media do not contain any exogenous growth factors, artificial stimulators of cellular proliferation, or undefined supplements. They are devoid of any protein kinase C stimulators and are suitable for the investigation of second messenger systems in the activation of human and murine lymphocytes. The formulations are complete and contain pharmaceutical grade human albumin, recombinant human insulin, and pasteurised human transferrin. All X-VIVO™ media products are manufactured under current GMPs and are listed with the FDA in a product master file.

X-VIVO™ 10
Supports the generation of LAK cells in a serum-free environment.

X-VIVO™ 15
Similar to X-VIVO™ 10 media composition
Optimised for the proliferation of tumour infiltrating lymphocytes (TIL) under serum-free conditions
Supports the proliferation of purified CD3+ cells isolated from peripheral blood and human tumours
Supports the growth of human monocytes, macrophage cells and cell lines, PBL, granulocytes, and natural killer (NK) cells.

X-VIVO™ 20
Used to successfully generate LAK cells from monocytedepleted peripheral blood lymphocytes (PBL) at high density
Used as a growth medium for PBL and tumour infiltrating lymphocytes (TIL).