Anti-GTP Cyclohydrolase 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-0136R-A680
: Bioss
- Antibody type:Primary
- Antigen name:GTP cyclohydrolase 1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:34-110/250
- Form:Liquid
- Gene ID:2643
- Antigen synonyms:GTP cyclohydrolase I|GTPCH 1|GCH 1|GTP CH I|GTP CH 1|Guanosine 5' triphosphate cyclohydrolase I.|DYT5|GCH1|GTPCH1|GTP-CH-1|GTP cyclohydrolase 1 dopa responsive dystonia|GTP cyclohydrolase 1|DYT 5|GCH
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:27 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human GTP-CH-1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyses the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesise tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Type: Primary
Antigen: GTP cyclohydrolase 1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 34-110/250
Host: Rabbit
Isotype: IgG
Reactivity: Mouse