Specifications
- Antibody type:Primary
- Antigen name:Calcium Channel, Voltage-dependent, P/Q type, alpha 1A subunit
- Antigen symbol:CACNA1A
- Clonality:Polyclonal
- Conjugation:Cy7®
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:773
- Antigen synonyms:EA2|HPCA|calcium channel|MHP1|voltage-dependent P/Q-type calcium channel subunit alpha-1A|APCA|L type|FHM|SCA6|voltage-gated calcium channel subunit alpha Cav2.1|brain calcium channel I|BI|MHP|CAV2.1|alpha-1 polypeptide|brain calcium channel 1|CACNL1A4
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CACNA1A
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat