Anti-GFPT2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

BOSSBS-13342R-HRP

Anti-GFPT2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

BOSSBS-13342R-HRP

Antibody type:
Primary
Antigen name:
Glutamine-fructose-6-phosphate transaminase 2
Antigen symbol:
GFPT2
Clonality:
Polyclonal
Conjugation:
HRP (Horseradish Peroxidase)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
9945
Antigen synonyms:
Glutamine:fructose 6 phosphate amidotransferase 2|Hexosephosphate aminotransferase 2|GFAT2|glutamine fructose 6 phosphate transaminase 2|D fructose 6 phosphate amidotransferase 2|GFPT2_HUMAN.|GFAT 2|Glucosamine fructose 6 phosphate aminotransferase [isomerizing] 2
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

GFPT2 (glutamine-fructose-6-phosphate transaminase 2), also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis. Expressed in spinal cord, heart and placenta, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation. Containing one glutamine amidotransferase type-2 domain and two SIS domains. GFAT2 is encoded by a gene that maps to human chromosome 5q35.3. GFAT2 gene variants have been linked to type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: GFPT2
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat